中国动脉硬化杂志2001，Vol.9Issue(2)：152-154,3.
Ⅱ型糖尿病家系中一级亲属的脂质代谢
紊乱与胰岛素抵抗
Dyslipidemia and Insulin Resistance of first Clegrr Retatives in 2 Type Diabetes Mullitus Families
摘要
Abstract
Aim To investigate the changes of lipid and the insulin-resistance non diabetes first degree relatives of 2 type diabetes mullitus families. Methods The fasting insulin (FINS), total cholesteral (TC), triglyceride (TG) and high density lipoprotein (HDL) were measured in diabetes mullitus (DM) group, impaired glucose tolerance (IGT) group and non diabetes first degree relatives (FDR) group of 2 type diabetes mellitus families. Their spouses were selected as control group. The oral glucose tolerance test (OGTT) were conducted in all grops. The insulin resistance were assessed by insulin sensitive index (ISI)=1/FPG (fasting plasme glucose) × FINS. Results TG in DM group, IGT group and FDR group was markedly elevated (P<0.01 and P<0.05）. HDL level and ISI in DM group, IGT group and FDR group were lower (P<0.05 and P<0.01）. Conclusion Insulin resistance and lipid abnormalities appear early (before the development of IGT and DM) in first degree relatives of 2 type DM.关键词
糖尿病,非胰岛素依赖型/脂代谢/胰岛素/一级亲属分类
医药卫生引用本文复制引用
王季猛,王建平,汪学军..Ⅱ型糖尿病家系中一级亲属的脂质代谢
紊乱与胰岛素抵抗[J].中国动脉硬化杂志,2001,9(2):152-154,3.
