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肝移植术后急性排斥反应的诊治(附2例报告)

张铁民 姜洪池 乔海泉 许军 葛淑芝 唐文燕 孙备

中国普通外科杂志2001,Vol.10Issue(2):152-154,3.
中国普通外科杂志2001,Vol.10Issue(2):152-154,3.

肝移植术后急性排斥反应的诊治(附2例报告)

Diagnosis and treatment of acute rejection of liver transplantation (a report of 2 cases)

张铁民 1姜洪池 1乔海泉 1许军 1葛淑芝 1唐文燕 1孙备1

作者信息

  • 1. 哈尔滨医科大学附属第一医院普外科,
  • 折叠

摘要

Abstract

Objective To investigate the diagnosis and treatment of acute rejection of orthotopic liver transplantation (OLT). Methods From July 1999 to April 2000, two piggyback liver transplantations were performed on two patients with Wilson's disease. Results Cyclosporine A, azathioprine and methylprednisolone were the baseline immunosuppression management. Acute rejection occured 5 times in the 2 patients. The correct diagnosis was obtained through clinical inspection, liver function test and biopsy. The rejections were controlled by intensive steriod therapy plus OKT3 or FK506. Conclusions Clinical inspection and liver function test can suggest the episode of acute rejection in time. Hepatic biopsy is the key point for diagnosis of acute rejecton, Reasonable use of immunosppression is critical for the treatment.

关键词

肝移植/副作用/移植物排斥

分类

医药卫生

引用本文复制引用

张铁民,姜洪池,乔海泉,许军,葛淑芝,唐文燕,孙备..肝移植术后急性排斥反应的诊治(附2例报告)[J].中国普通外科杂志,2001,10(2):152-154,3.

中国普通外科杂志

1005-6947

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