中德临床肿瘤学杂志（英文版）2009，Vol.8Issue(3)：152-155,4.DOI:10.1007/s10330-009-0002-1
CT增强双期扫描在肺癌非手术治疗疗效评价中的初步研究
Preliminary assessing no-surgical treatment response in bronchogenic carcinoma with double-phase contrast material-enhanced computed tomography
Shenjiang Li 1Yong Zhao 1Yan Zhu 1Feng Zhu 1Debin Liu 1Wenjie Liang 1Xuefeng Cui 1Wenjie Bi1
作者信息
- 1. Department of Imageology, The Eighty-eighth Military Hospital, Tai'an 271000, China
- 折叠
摘要
Abstract
Objective: To evaluate the efficacy of double-phase contrast material-enhanced computed tomography (CT) in assessing no-surgical treatment response in bronchogenic carcinoma preliminarily. Methods: 52 patients with bronchogenic carcinoma after no-surgical treatment underwent double-phase contrast material-enhanced computed tomography. Two spiral CT scans were obtained at 25 and 90 seconds respectively after nonionic contrast material was administrated via the antecubital vein at a rate of 4 mL/s by using an autoinjector. Precontrast and postcontrast attenuation on every scan was recorded and peak height was calculated. Enhancement pattern was evaluated on the images obtained at 25 and 90 seconds after injection of contrast medium. Results: Precontrast attenuation, postcontrast attenuation at 25 and 90 seconds were 42.20±7.43 Hu, 57.35 ± 10.09 Hu and 71.85 ± 12.45 Hu, respectively. No statistically significant difference in precontrast attenuation was found between our results in the study and the results in our old study (mean precontrast attenuation 40.70 Hu) which was obtained in cases before therapy (t = 1.455, P = 0.152 ＞ 0.05). Peak height of bronchogenic carcinoma after no-surgical treatment (29.46 ± 10.85 Hu) were significantly lower than that of bronchogenic carcinoma before therapy obtained in our old study (mean peak height 35.79 Hu; t = 4.206, P = 0.001 ＜ 0.05). 32 of 52 cases showed homogeneous enhancement at 90 seconds. Of the 32 cases, there were 21 with inhomogeneous enhancement, 7 with inhomogeneous enhancement, 2 with central enhancement and 2 with peripheral enhancement at 25 seconds. Conclusion: Bronchogenic carcinoma after no-surgical treatment shows a gradual increase to the peak height after administration of contrast material. Peak heights can reflect the blood supply of bronchogenic carcinoma and might be index for evaluation of no-surgical treatment response in bronchogenic carcinoma.关键词
bronchogenic carcinoma/tomography, X-ray computed/evaluation of therapeutic effectKey words
bronchogenic carcinoma/tomography, X-ray computed/evaluation of therapeutic effect分类
医药卫生引用本文复制引用
Shenjiang Li,Yong Zhao,Yan Zhu,Feng Zhu,Debin Liu,Wenjie Liang,Xuefeng Cui,Wenjie Bi..CT增强双期扫描在肺癌非手术治疗疗效评价中的初步研究[J].中德临床肿瘤学杂志（英文版）,2009,8(3):152-155,4.
