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首页|期刊导航|硅酸盐学报|羟基磷灰石/外消旋聚乳酸复合材料的制备、力学性能及体外降解

羟基磷灰石/外消旋聚乳酸复合材料的制备、力学性能及体外降解

王欣宇 单学智 韦明 韩颖超 李世普

硅酸盐学报2007,Vol.35Issue(11):1538-1540,1545,4.
硅酸盐学报2007,Vol.35Issue(11):1538-1540,1545,4.

羟基磷灰石/外消旋聚乳酸复合材料的制备、力学性能及体外降解

PREPARATION, MECHANICAL PROPERTIES AND IN VITRO DEGRADATION OF HYDROXYAPATITE/POLY-RACEMIC LACTIC ACID COMPOSITE

王欣宇 1单学智 1韦明 1韩颖超 1李世普1

作者信息

  • 1. 武汉理工大学生物材料与工程研究中心,武汉,430070
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摘要

Abstract

A hydroxyapatite/poly-D, L (racemic) lactic acid (HA/PDLLA) composite was prepared by recombination of liquid-phase adsorption. The mechanical properties of the composite were determined, and the degradation of the composite was investigated via simulation in vitro. Results illustrate that the mechanical properties of the composite are improved with a bending strength of 146.2 Mpa,a bend modulus of 2.5 Gpa, due to the addition of 10% mass fraction of HA particles into the composite. Compared with pure PDLLA material, the bending strength is increased 9.4 Mpa, the bending modulus is increased 0.2 Gpa, and the decline of the tensile strength of the composite is not obvious. The mass loss of the 90% PDLLA/10% HA composite was less than 1% during the initial 6 weeks, and the fmal mass loss was 5.4% at the 12th week. The mass loss of the composite was smaller than that of pure PDLLA material by about 2%-3% in the mid-later period of degradation.

关键词

羟基磷灰石/外消旋聚乳酸复合材料/制备/力学强度/降解

Key words

hydroxyapatite/poly-racemic lactic acid composite/preparation/mechanical strength/degradation

分类

通用工业技术

引用本文复制引用

王欣宇,单学智,韦明,韩颖超,李世普..羟基磷灰石/外消旋聚乳酸复合材料的制备、力学性能及体外降解[J].硅酸盐学报,2007,35(11):1538-1540,1545,4.

基金项目

国家自然科学基金(50472041)资助项目. (50472041)

硅酸盐学报

OA北大核心CSCDCSTPCD

0454-5648

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