中华医学杂志（英文版）2002，Vol.115Issue(10)：1538-1541,4.
应用Cox模型分析影响胆管癌切除术后的预后因素
Multivariate analysis by Cox Proportional Hazards Model on pro gnoses of patients with bile duct carcinoma after resection
何平 1石景森 1陈武科 1王作仁1
作者信息
- 1. 西安交通大学第一医院肝胆外科研究室,西安,710061
- 折叠
摘要
Abstract
Objective To evaluate the influence of various clinicopathologic factors on the survival of patients with bile duct carcinoma after curative resection.Methods A retrospective analysis was performed on 86 cases of bile duct carcinoma treated from January 1981 to September 1995. Fiftee n clinicopathologic factors that could possibly influence survival were selected . A multivariate analysis of these individuals was performed using the Cox Prop ortional Hazards Model.Results The overall cumulative survival rate was 73% f or 1 year, 32% for 3 years and 19% for 5 years. The results of univariate analy sis showed that the major significant prognostic factors for influencing surviva l of these patients were type of histological lesion, lymph node metastasis, pan creatic invasion, duodenal invasion, perineural invasion, macroscopic vessel involvement, resected surgical margin and depth of cancer invasion (P<0.05). Pancreatic invasion, perineural invasion and lymph node metastases were the thre e most important prognostic factors determined by multivariate analysis using the Cox Proportional Hazards Model.Conclusion Pancreatic invasion, perineural invasion an d lymph node metastases are the most important prognostic factors for bile duct carcinoma after curative resection.关键词
胆管癌 Cox比例风险模型 预后Key words
biliary tract neoplasms/Cox Proport ional Hazards Model/prognosis分类
医药卫生引用本文复制引用
何平,石景森,陈武科,王作仁..应用Cox模型分析影响胆管癌切除术后的预后因素[J].中华医学杂志（英文版）,2002,115(10):1538-1541,4.
