北京大学学报（医学版）2001，Vol.33Issue(2)：160-163,4.
幽门螺杆菌感染与胃癌及胃部病变的多组病例对照研究
Multi-groups controled study on the association of Helicobacter pylori infection with gastric cancer and stomach diseases
蒋咏文 1王润田 1王涛 1张洁苹 1雷道年2
作者信息
- 1. 北京大学公共卫生学院流行病学与卫生统计学系，北京 100083
- 2. 北京大学基础医学院病理学系，北京 100083
- 折叠
摘要
Abstract
Objective: This multi-group case control study was performed to determine whether Helicobacter pylori infection was associated with gastric cancer and stomach diseases. Methods: Gastric cancer and stomach disease patients that were diagnosed pathologically between 1994 and 1996 years were divided into several case groups and control group, all histological specimens collected in gastric cancer high risk region of Shandong Province were used to measure exposure history. Results: After variables concerning age, sex and education were adjusted, odds ratios of chronic superficial gastritis in antrum, peptic ulcer disease and active degree of inflammation associated with H. pylori infection remained significant (OR was 2.072, 2.980, 2.086 respectively). Correlation analyses showed negative relationship between degree of stomach diseases and H. pylori infection(r=－0.217). Conclusion: The results support the hypothesis of a relationship between H. pylori infection and the development of chronic superficial gastritis in antrum, peptic ulcer disease and active degree of inflammation.关键词
螺杆菌,幽门/胃肿瘤/流行病学/病例对照研究/胃疾病/流行病学分类
医药卫生引用本文复制引用
蒋咏文,王润田,王涛,张洁苹,雷道年..幽门螺杆菌感染与胃癌及胃部病变的多组病例对照研究[J].北京大学学报（医学版）,2001,33(2):160-163,4.
