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水牛角不同相对分子质量酶解液的药理作用研究

李宝国 黄丽华 杜雪 曲东平 张孝卫

中国当代医药2009,Vol.16Issue(13):16-17,2.
中国当代医药2009,Vol.16Issue(13):16-17,2.

水牛角不同相对分子质量酶解液的药理作用研究

Studies on pharmacological effects of different molecular weight enzymolysis liquid from cornu bubali

李宝国 1黄丽华 2杜雪 2曲东平 2张孝卫2

作者信息

  • 1. 山东中医药大学,山东济南,250000
  • 2. 济南市卫生科技交流服务中心,山东济南,250000
  • 折叠

摘要

Abstract

Objective: To study the pharmacological effects of different molecular weight enzymolysis liquid from cornu bubali. Methods: It was observed to research the pharmacological effects of different molecular weight enzymolysis liquid that the influence and action of mice to the pentobarbitol sodium hypnosis, LPS caused death, coagulation time, sponta-neous activity, anti-infection and so on. Results: Compared with the NS control group, <3 kD and the 10-30 kD enzymoly-sis fluid had obvious sedative effect (P<0.01). The<3 kD group had remarkable resistance to LPS caused death (P<0.05). The >30 kD group had obvious hemostatic function (P<0.01).The 5-10 kD group had obvious inhibition to the spontaneous activity (P<0.01).The 5-10 kD group and the 10-30 kD group had obvious enhancement to the anti-infection (P<0.01). Conclusion: The different molecular weight enzymolysis liquid from cornu bubali has different pharmacological effects.

关键词

水牛角/相对分子质量/酶解液/药理作用

Key words

Cornu bubali/ Different molecular weight/ Enzymolysis liquid/ Pharmacological effects

分类

医药卫生

引用本文复制引用

李宝国,黄丽华,杜雪,曲东平,张孝卫..水牛角不同相对分子质量酶解液的药理作用研究[J].中国当代医药,2009,16(13):16-17,2.

基金项目

济南市卫生局课题资助(项目编号:济卫科计2006-35) (项目编号:济卫科计2006-35)

中国当代医药

1674-4721

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