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限食对高脂饮食大鼠体重、血脂及血糖的影响

杜建海 陈红梅 蔺美玲 张小郁 郑天珍 李伟 瞿颂义

兰州大学学报(医学版)2009,Vol.35Issue(2):16-19,4.
兰州大学学报(医学版)2009,Vol.35Issue(2):16-19,4.

限食对高脂饮食大鼠体重、血脂及血糖的影响

Effects of restricting food on body mass,blood lipid and glucose of rats

杜建海 1陈红梅 1蔺美玲 1张小郁 1郑天珍 1李伟 1瞿颂义1

作者信息

  • 1. 兰州大学,基础医学院,兰州大学,甘肃省新药临床前研究重点实验室,甘肃,兰州,730000
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摘要

Abstract

Objective To study the effects of restricting food on body mass and lipid metabolism of rats,and provide theoretic evidence for dietary therapy of obesity. Methods Healthy SD rats were randomly divided into 3 groups,normal control group given normal chow diet,high-fat diet group given high-fat diet and restricting food group given 60% diet of the high-fat diet group. The body mass was weighed every week in the above 3 groups. The serum lipids and glucose levels were detected after 7 weeks of feeding. Results When compared with normal control group,rats in high-fat diet group displayed increased body mass,enhanced levels of serum lipid and glucose. When compared with high-fat diet group,rats in restricting food group displayed decreased body mass and level of serum lipid. Conclusion Restricting food can reduce body mass,partly decrease serum lipid level,and improve lipid metabolism.

关键词

限食/高脂饮食/体重/大鼠

Key words

restricting food/high-fat diet/body mass/rat

分类

医药卫生

引用本文复制引用

杜建海,陈红梅,蔺美玲,张小郁,郑天珍,李伟,瞿颂义..限食对高脂饮食大鼠体重、血脂及血糖的影响[J].兰州大学学报(医学版),2009,35(2):16-19,4.

基金项目

国家自然科学基金(30572428) (30572428)

兰州大学学报(医学版)

OACSTPCD

1000-2812

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