中国药房2009，Vol.20Issue(21)：1622-1624,3.
藏妇康栓对实验性阴道炎的治疗作用研究
Therapeutical Effect of Zangfukang Suppository on Experimental Vaginitis in Rats
戴瑛 1张白嘉 1赵军宁 1边巴次仁 2索朗 2德吉 2王晓东 1邓治文1
作者信息
- 1. 四川省中医药科学院药理毒理研究所/国家中医药管理局中药质量生物学评价重点研究室,成都市,610041
- 2. 西藏自治区藏医院/西藏自治区藏医药研究院,拉萨市,850000
- 折叠
摘要
Abstract
OBJECTIVE: To evaluate the therapeutic effect of Zangfukong suppository on the experimental vaginitis. METHODS: The experimental rats were equally assigned to 6 groups: normal control group, model control group, gyno-dak-injected into the vigina of the estrous rats to establish colpomycosis model. The effect of gangfukang suppository on the infection rate of candida albicans was observed. The bacterial vaginitis model was established by injecting the mixture bacteria of Neisseria gonorrhoeae, staphylococcus aureus and escherichia coli into the vagina of rats, and the effect of Zangfukang suppository on the gonococcal infection rate.RESULTS: After local application of Zangfukang suppository for 7 consecutive days for treatment of colpitis mycotica of rats, the infection rates of candida albicans were significantly lower in medium- dose and high - dose groups than in the model control group(P<0.05) .After local application of Zangfukang suppository for 6 consecutive days for treatment of bacterial vaginitis,and the positive rates of neisseria gonorrhoeae in vaginal secretions in medium - dose and high - dose groups were significantly lower than in the model control group(P<0.05 or P<0.01) .CONCLUSION: Locally application of gang-fukang suppository showed remarkable therapeutic efficacy for both the experimental vaginal candidiasis and bacterial vaginitis of rats.关键词
藏妇康栓/霉茵性阴道炎/细茵性阴道炎/实验研究/大鼠Key words
Zangfukang vaginal suppository/Mycotic vaginitis/Bacterial vaginitis/Empirical study/Rats分类
医药卫生引用本文复制引用
戴瑛,张白嘉,赵军宁,边巴次仁,索朗,德吉,王晓东,邓治文..藏妇康栓对实验性阴道炎的治疗作用研究[J].中国药房,2009,20(21):1622-1624,3.
