摘要
Abstract
BACKGROUND: Osteophyte caused by degenerative osteoarthropathy of the cervical vertebrae may compress the vertebral artery, resulting in vertebrobasilar insufficiency, especially when the patients' head postures change, making them adapt forced head position.OBJECTIVE: To investigate successively the relationship between the change of flow velocity of the posterior circulation and the symptom of vertebrobasilar insufficiency during various head postures with transcranial Doppler ultrasound.DESIGN: Randomized grouping controlled, auto-control observation.SETTING: Department of Neurology, Guangxi Minzu Hospital and Department of Neurology, First Hospital, Peking University.PARTICIPANTS: A total of 20 patients with vertebrobasilar insufficiency and 10 normal persons were enrolled from Department of Neurology,Guangxi Minzu Hospital between March 2003 and May 2004.METHODS: Regard blood flow velocity in natural position of anterior segment of posterior cerebral artery as baseline values. Blood flow velocity was compared at left rotation, right rotation, anterior inflexion and posterior inflexion. Symptoms of vertebrobasilar insufficiency were observed. The data were collected and compared in individuals, within group, and between groups.MAIN OUTCOME MEASURES: Blood flow velocity difference of various head postures in each group; Symptoms of vertebrobasilar insufficiency were observed.RESULTS:During monitoring, there were 9 cases complained of ischemic symptoms and 11 cases without symptoms. There was no significant difference in blood flow change of left rotation, right rotation and posterior inflexion in the normal control group with natural position. The reduction of flow velocity was significant in anterior inflexion (P ＜ 0.05 ), and none appeared clinical symptom. There was significant difference in reduction of blood flow at anterior inflexion and at natural position in patients with symptom (P ＜ 0.05), and there was significant difference in reduction of blood flow at posterior inflexion and natural position (P ＜ 0.001 ). There was significant difference in reduction of blood flow at left rotation and posterior inflexion in those without symptom during monitoring as compared with that at natural position (P ＜ 0.05 ).CONCLUSION: Continuously observing the blood flow in posterior cerebral artery at different head position can objectively assess the relationship between decrease of blood flow velocity of vertebral arteries induced by neck movements and clinical symptoms.关键词
大脑后动脉/血流速度/经颅多普勒超声分类
医药卫生
