中国临床康复2005，Vol.9Issue(39)：166-167,2.
中国朝鲜族人群6个短串联重复序列位点的遗传多态性
Genetic polymorphism of 6 short tandem repeat loci in Chinese korean
摘要
Abstract
BACKGROUND: Many scholars have reported the study of genetic polymorphism of short tandem repeat loci in different countries, areas, and population. But what is the genetic polymorphism of short tandem repeats loci of Chinese Korean is still unknown.OBJECTIVE:To investigate the distribution of the genetic polymorphism of D16S539 D7S820, D13S317, CSF1PO, TPOX and TH01 in Chinese Korean, obtain the crowded genetic data of corresponding polymorphism loci.DESIGN: Single sample observation.SETTING: Staff Room of Biology, Department of Detecting and Analyzing DNA, Mudanjiang Medical College.MATERIALS: Periphoral blood samples from 100 unrelated individuals in Korean of Mudanjiang were chosen from January 2001 to February 2001.METHODS: Genotype detection was performed in one hundred unrelated individuals with polymerase chain reaction amplification fragment length polymorphism analysis.MAIN OUTCOME MEASURES: Sample genotype of D16S539,D7S820, D13S317, CSF1PO, TPOX, THO1 6 short tandem repeat loci.TH01 locus.CONCLUSION: The genotypes distributions of the 6 short tandem repeat (STR) in Chinese Korean met Hardy-Weinberg equilibrium, and have higher heterozygosities. The gene frequency and other data obtained can provide the basis for studying the crowded genetics of Chinese Korean.关键词
短串重复序列/遗传多态性/聚合酶链反应分类
医药卫生引用本文复制引用
卜晓波,王英,宋洁,李秀芝,包海花,张书捷,高雪玲..中国朝鲜族人群6个短串联重复序列位点的遗传多态性[J].中国临床康复,2005,9(39):166-167,2.基金项目
黑龙江省自然科学基金资助项目(D0259) （D0259）
黑龙江省普通高校骨干教师创新能力自助计划 （）
黑龙江省卫生厅自然科学基金(200-082)the National Natural Science Foundation of Heilongjiang Province, No.D0259 （200-082）
the Grants from the Foundation for University Key Teachers in Innovation Capacity Self-help Project （）
Natural Science Foundation of Ministry of Health of Heilongjiang Province, No.200-082 （）
