中华医学杂志（英文版）2002，Vol.115Issue(11)：1675-1678,4.
伴自杀行为史的情感障碍患者感觉性诱发电位初探
Sensory evoked potentials in patients with affective disorders accompanying suicidal behavior
摘要
Abstract
Objective To investigate the variations of sensory evoked potentials (SEPs) in patients with affective disorders accompanying suicidal behavior. Methods 39 depressive patients, 22 manic patients and 33 normal controls were included in the study. Visual, auditory and somatosensory evoked potentials (VEP, AEP & SSEP) were recorded from every subject using a Nicolet Spirit Instrument. Results Both the depressive and manic groups presented prolonged latencies and decreased amplitudes of major components of SEPs as compared to that of normal controls. Depressive patients with suicidal behavior had decreased P3 amplitude of VEP (P<0.05), while maniacs with suicidal behavior had decreased P2 amplitudes of VEP & AEP (P<0.05 or 0.01). Compared with patients without suicidal behavior, patients with suicidal behavior had significantly decreased P3 amplitudes of VEP & SSEP. Conclusions The variations of SEPs in patients with affective disorders is closely associated with a history of suicidal behavior. Their clinical significance and biological correlates with suicidal behavior need further study.关键词
情感障碍/诱发电位/自杀Key words
affective disorders/evoked potentials/suicide分类
医药卫生引用本文复制引用
王红星,陈兴时,白培深,尹岭..伴自杀行为史的情感障碍患者感觉性诱发电位初探[J].中华医学杂志（英文版）,2002,115(11):1675-1678,4.基金项目
The study was supported by National Key Program for Basic Research of China (No. 2001CCA00700). （No. 2001CCA00700）
