首页|期刊导航|南京医科大学学报(英文版)|Chemical composition and antimicrobial activity of essential oil isolated from the cultured mycelia of Ganoderma japonicum
南京医科大学学报(英文版)2009，Vol.23Issue(3)：168-172,5.
Chemical composition and antimicrobial activity of essential oil isolated from the cultured mycelia of Ganoderma japonicum
Chemical composition and antimicrobial activity of essential oil isolated from the cultured mycelia of Ganoderma japonicum
摘要
Abstract
Objective:To explore a new natural antibiotic. Methods:The chemical composition of the essential oil from Ganoderma japonicum (G. japonicum) mycelia was analyzed by gas chromatography-mass spectrometry(GC-MS). The antimicrobial activity of the oil was evaluated against eighteen microorganisms, including bacteria, mildew and yeast by using a disc diffusion method. Furthermore, the minimum inhibitory concentrations(MIC) and the minimum bactericidal concentrations(MBC) of the essential oil against twelve clinical pathogens were determined. Results:The main components of the oil were nerolidol, decadienal, linaiool and benzyl alcohol. The antimicrobial results indicated that the oil inhibited all the tested bacterium, especially Methicillin-resistant Staphylococcus aureus (MRSA) in which the antibacterial activity exhibited a MBC of 1.03 mg/ml. Conclusion: The essential oil of G.japonicum mycelium has significant inhibitory activity. It is a potential medicinal resource that can be used as a natural antibiotic.关键词
Ganoderma japonicum/ essential oil/ antimicrobial activity/ clinical pathogensKey words
Ganoderma japonicum/ essential oil/ antimicrobial activity/ clinical pathogens分类
医药卫生引用本文复制引用
Dandan Liu,Zheng Hu,Zhigang Liu,Bo Yang,Wenjuan Tu,Liang Li..Chemical composition and antimicrobial activity of essential oil isolated from the cultured mycelia of Ganoderma japonicum[J].南京医科大学学报(英文版),2009,23(3):168-172,5.基金项目
This work was supported by the Natural Science Foundation of Hubei Province (2004ABA228). （2004ABA228）
