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首页|期刊导航|基础医学与临床|溃疡性结肠炎患者血清超氧化物歧化酶及脂质过氧化物的变化

溃疡性结肠炎患者血清超氧化物歧化酶及脂质过氧化物的变化

吕永慧 陈文剑

基础医学与临床2001,Vol.21Issue(2):169-171,3.
基础医学与临床2001,Vol.21Issue(2):169-171,3.

溃疡性结肠炎患者血清超氧化物歧化酶及脂质过氧化物的变化

Changes of superoxide dismutase and lipid peroxide in blood serum ulcerative of colitis patient

吕永慧 1陈文剑1

作者信息

  • 1. 广州市中医医院消化内科,
  • 折叠

摘要

Abstract

The content of superoxide dismutase (SOD) and lipid peroxide (LPO) of blood serum in 120 ulcerative colitis (UC) patient were tested by means of xanthine oxidation method and colorimeter on the reactive product of thio-barbituric acid.The content of SOD in the UC Patients was lower than that in the normal control group (P<0.001),and the content of LPO in the UC patients was obviously higher than that the control group (P<0.001).The content of SOD in the UC patients which accompanied the types of simple retention of damp-heat in the interior or weakness of the spleen and the stomach or the stagnancy of qi and blood stasis or deficiency of yin and stagnancy of qi and blood stasis was distinctly lower tban the one in the normal control groups (P<0.001).The content of LPO in them is distinctly higher than the content of LPO in normal control group (P<0.001).Conclusion: These results suggested that the content of SOD of protecting cell factor in the body of ulcerative colitis patients who were mostly the type of retention of damp-heat in the interior decreased and the content of LPO of damaging cell factor increased.When the patients accompanied with the deficiency,the content of the SOD in them reduced remarkably and the content of LPO enhanceed remarkably,especially in those who are the type of weekness of the spleen and the stomach or insufficiency of the spleen and the stagnancy of qi and blood stasis.

关键词

溃疡性结肠炎/超氧化物歧化酶/脂质过氧化物

分类

医药卫生

引用本文复制引用

吕永慧,陈文剑..溃疡性结肠炎患者血清超氧化物歧化酶及脂质过氧化物的变化[J].基础医学与临床,2001,21(2):169-171,3.

基金项目

广东省科委九五重点科技项目(No.粤科技字[1995]1号) (No.粤科技字[1995]1号)

基础医学与临床

OA北大核心CSCD

1001-6325

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