中国药理学通报2001，Vol.17Issue(1)：17-20,4.
内吗啡肽研究进展
Progress in the studies of endomorphins
任维华 1霍笑风 1吴宁 1王锐1
作者信息
- 1. 兰州大学生命科学院生物化学与分子生物学系,
- 折叠
摘要
Abstract
Endomorphins(EMs),two tetrapeptides, were discovered in 1997 and believed to be endogenous ligands of μ-opioide receptor(MOR). They mediated various physiological processes by binding to MOR that couple with G-proteins. Based on our works and literatures, we reviewed the distribution in nerve system, receptor binding properties, analgesis, effects on ion channels, conformation and struction-activity relationship of EMs.关键词
内吗啡肽/μ阿片受体/受体结合特性/构效关系分类
医药卫生引用本文复制引用
任维华,霍笑风,吴宁,王锐..内吗啡肽研究进展[J].中国药理学通报,2001,17(1):17-20,4.
