中德临床肿瘤学杂志（英文版）2009，Vol.8Issue(3)：172-174,3.DOI:10.1007/s10330-008-0162-4
三维适形放疗配合全脑照射治疗脑转移瘤的疗效观察
The effects of three-dimensional conformal radiotherapy combined with whole brain irradiation on brain metastases
Jin Hu 1Yeqing Zhou 1Mi Liu1
作者信息
- 1. Department of Radiotherapy, The Affiliated Hospital of North Sichuan Medical College, Sichuan 637000, China
- 折叠
摘要
Abstract
Objective: To observe the recently therapeutic effects and toxicity of three-dimensional conformal radiotherapy combined with whole brain irradiation for patients with brain metastasis. Methods: 33 cases were treated by whole brain irradiation at first, the dose of which was 36-40 Gy (18-20 f). Then three-dimensional conformal radiotherapy was added to the focus with a total dose of 20-25 Gy, whose fractionated dose was 2-5 Gy/time, 5 times/week or 3 times/week. Results: Within 1 month after radiotherapy, according to imaging of the brain, the CR of all patients was 45.5%, PR 36.4%, NC 15.1%, and PD 3%. For the 32 cases with neural symptoms before radiation, the CR of the symptoms was 40.6% and PR 59.4%. All patients gained different increases in KPS grade. By the end of the follow-up period, there were 22 deaths with the mean survival time up to 9.3 months. Conclusion: Three-dimensional conformal radiotherapy combined with whole brain irradiation can not only effectively control brain metastases and improve life quality, but also tends to prolong survival time.关键词
brain metastasis/three-dimensional conformal radiotherapy/whole brain irradiation/effectKey words
brain metastasis/three-dimensional conformal radiotherapy/whole brain irradiation/effect分类
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Jin Hu,Yeqing Zhou,Mi Liu..三维适形放疗配合全脑照射治疗脑转移瘤的疗效观察[J].中德临床肿瘤学杂志（英文版）,2009,8(3):172-174,3.
