老年心脏病学杂志（英文版）2005，Vol.2Issue(1)：17-22,6.
Percutaneous coronary interventions in the elderly:a 10- year experience in Northern New England
Percutaneous coronary interventions in the elderly:a 10- year experience in Northern New England
David J. Malenka 1James T. DeVries 2Samuel J. Shubrooks Jr3
作者信息
- 1. Center for the Evaluative Clinical Sciences,Dartmouth Medical School, Hanover , NH, USA
- 2. Section of Cardiology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA
- 3. Division of Cardiology, Beth Israel-Deaconess Medical Center, Boston, MA, USA
- 折叠
摘要
Abstract
Background There is a paucity of information available for clinical decision making applying to the elderly patient population. Therefore, data of percutaneous coronary interventions (PCI) including demographic information on the elderly patients, procedural practices, and outcomes are needed. Objectives and Methods From consecutive PCIs of participating institutions, demographics data, clinical, angiographic success and adverse clinical outcomes were collected. Standard statistical methods were used to compare crude differences in patient and procedural characteristics across age groups. Results At baseline, the prevalence of comorbid conditions ( renal failure and heart failure) increased with age. Unstable angina or a non-ST elevation MI were the most common indications for PCI across all age groups. Fewer patients ≥ 80 years old were undergoing primary PCI and older patients were somewhat less likely to receive a Ⅱb/Ⅲa receptor blocker. Slightly more patients ≥ 80 years old underwent a 2-vessel PCI ( consistent with them having more multivessel disease) and these patients were more likely to have an intervention on a Type C lesion. Compared to patients ＜ 50 years old, those aged ≥ 70 years old had a significantly increased risk of death, MI, stroke, or vascular complications at the access site. Conclusions This study suggests increasing age is associated with increasing risk for an adverse outcome following PCI. This is in part attributable to case-mix but likely, also related to the changing physiology of aging. Despite the increased risk of the procedure, the clinical success rate for PCI is quite high and makes it a reasonable alternative for the treatment of CAD in the elderly.关键词
coronary artery disease/elderly/percutaneous coronary interventionKey words
coronary artery disease/elderly/percutaneous coronary intervention分类
医药卫生引用本文复制引用
David J. Malenka,James T. DeVries,Samuel J. Shubrooks Jr..Percutaneous coronary interventions in the elderly:a 10- year experience in Northern New England[J].老年心脏病学杂志（英文版）,2005,2(1):17-22,6.
