中华医学杂志（英文版）2004，Vol.117Issue(2)：176-182,7.
Prognostic value of Doppler transmitral filling patterns in patients with chronic heart failure
Prognostic value of Doppler transmitral filling patterns in patients with chronic heart failure
ZHENG Zhe-lan郑哲岚 1A.Meissner 2B.Hausmann 2H.Alexander 2R.Simon3
作者信息
- 1. Department of Ultrasonography, First Affiliated Hospital, Zhejiang University College of Medicine, Hangzhou 310003, China
- 2. Department of Cardiology, Kiel University Hospital, Germany
- 3. Department of Cardiology, Kiel University Hospital, Germany
- 折叠
摘要
Abstract
Background Chronic heart failure is a significant cause of cardiovascular morbidity and mortality.This study tested the hypothesis that restrictive filling pattern may provide useful prognostic data for identifying patients with chronic heart failure at high risk of all-cause cardiac death.Methods Ninety patients with chronic heart failure [70 men and 20 women, mean age (58.1±11.6) years] were investigated and followed for (18. 8±7. 9) months. During this period, 14 patients died of progressive pump failure, 12 patients underwent heart transplantation, 5 patients died suddenly, and 2 patients died of acute myocardial infarction. A new criterion, the restrictive filling index (RFI), was designed to subgroup patients into a restrictive and a nonrestrictive group.Results Patients with restrictive filling pattern had a more severe left ventricular dysfunction and a higher cardiac mortality. Analysis by the Kaplan-Meier method revealed that patients in the RFI≥1 and RFI＜1 groups had a cardiac events-free survival rate of 52% versus 94% at 1 year, and 27. 5% versus 92% at 2 years, respectively. The multivariate Cox proportional hazard model selected RFI as the most powerful prognostic factor (χ2 =8. 8017, P =0. 0030) for all-cause cardiac death.关键词
prognosis/echocardiography, Doppler/heart failure, congestive/blood flow velocityKey words
prognosis/echocardiography, Doppler/heart failure, congestive/blood flow velocity分类
医药卫生引用本文复制引用
ZHENG Zhe-lan郑哲岚,A.Meissner,B.Hausmann,H.Alexander,R.Simon..Prognostic value of Doppler transmitral filling patterns in patients with chronic heart failure[J].中华医学杂志（英文版）,2004,117(2):176-182,7.
