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首页|期刊导航|中华医学杂志(英文版)|Protective effects of vitamin B12, ginseng saponin, and folic acid against murine fetal deformities caused by hyperthermia

Protective effects of vitamin B12, ginseng saponin, and folic acid against murine fetal deformities caused by hyperthermia

李荷莲 王博蔚 赵丹 韩丽英

中华医学杂志(英文版)2003,Vol.116Issue(11):1776-1778,3.
中华医学杂志(英文版)2003,Vol.116Issue(11):1776-1778,3.

Protective effects of vitamin B12, ginseng saponin, and folic acid against murine fetal deformities caused by hyperthermia

Protective effects of vitamin B12, ginseng saponin, and folic acid against murine fetal deformities caused by hyperthermia

李荷莲 1王博蔚 1赵丹 2韩丽英3

作者信息

  • 1. Department of Gynecology and Obstetrics, Second Hospital of Jilin University, Changchun 130021, China
  • 2. Department of Gynecology and Obstetrics, First Hospital of Baotou Medical College, Baotou 014010, China
  • 3. Department of Gynecology and Obstetrics, Second Hospital of Jilin University, Changchun 130021, China
  • 折叠

摘要

Abstract

Objective To investigate the protective effects of vitamin B12, ginseng saponin, and folic acid on mouse embryos subjected to high heat.Methods Mice were used for the experiment.Results After exposure of pregnant mice to high heat, the rates of teratism, stillbirth, and fetal absorption were markedly lower in mice treated with ginseng saponin and folic acid following heat exposure than in untreated mice. There were no significant differences in these rates when comparing mice treated with vitamin B12 with the untreated mice.Conclusions Ginseng saponin and folic acid can lessen injuries to murine embryos caused by high heat, while vitamin B12 has little protective effect against high temperature except for promoting overall embryonic growth.

关键词

embryo * hyperthermia * deformity * vitamin B12 * folic acid * ginseng saponin

Key words

embryo * hyperthermia * deformity * vitamin B12 * folic acid * ginseng saponin

分类

医药卫生

引用本文复制引用

李荷莲,王博蔚,赵丹,韩丽英..Protective effects of vitamin B12, ginseng saponin, and folic acid against murine fetal deformities caused by hyperthermia[J].中华医学杂志(英文版),2003,116(11):1776-1778,3.

基金项目

This work was supported by a grant from the National Natural Science Fundation of China (No. 39470725). (No. 39470725)

中华医学杂志(英文版)

OAMEDLINESCI

0366-6999

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