首页|期刊导航|中华医学杂志(英文版)|Protective effects of vitamin B12, ginseng saponin, and folic acid against murine fetal deformities caused by hyperthermia
中华医学杂志(英文版)2003,Vol.116Issue(11):1776-1778,3.
Protective effects of vitamin B12, ginseng saponin, and folic acid against murine fetal deformities caused by hyperthermia
Protective effects of vitamin B12, ginseng saponin, and folic acid against murine fetal deformities caused by hyperthermia
摘要
Abstract
Objective To investigate the protective effects of vitamin B12, ginseng saponin, and folic acid on mouse embryos subjected to high heat.Methods Mice were used for the experiment.Results After exposure of pregnant mice to high heat, the rates of teratism, stillbirth, and fetal absorption were markedly lower in mice treated with ginseng saponin and folic acid following heat exposure than in untreated mice. There were no significant differences in these rates when comparing mice treated with vitamin B12 with the untreated mice.Conclusions Ginseng saponin and folic acid can lessen injuries to murine embryos caused by high heat, while vitamin B12 has little protective effect against high temperature except for promoting overall embryonic growth.关键词
embryo * hyperthermia * deformity * vitamin B12 * folic acid * ginseng saponinKey words
embryo * hyperthermia * deformity * vitamin B12 * folic acid * ginseng saponin分类
医药卫生引用本文复制引用
李荷莲,王博蔚,赵丹,韩丽英..Protective effects of vitamin B12, ginseng saponin, and folic acid against murine fetal deformities caused by hyperthermia[J].中华医学杂志(英文版),2003,116(11):1776-1778,3.基金项目
This work was supported by a grant from the National Natural Science Fundation of China (No. 39470725). (No. 39470725)