中国临床康复2004，Vol.8Issue(1)：183-185,3.
血脂代谢紊乱与中青年脑梗死危险因素的相关性分析
The relationship between serum lipid metabolic dysfunction and cerebral infarction in middle age and youth
吴军 1赵水平 2郭纯 3蒋波 1谭利明 1肖志杰1
作者信息
- 1. 中南大学湘雅二院神经内科,湖南省长沙市,410011
- 2. 中南大学湘雅二院心内科,湖南省长沙市,410011
- 3. 常德市三医院检验科,湖南省常德市,415000
- 折叠
摘要
Abstract
AIM:To explore the relationship between serum lipid and cerebral infarction in middle age and youth. METHODS:Blood samples were collected from 111 middle-aged and young patients with cerebral infarction and 80 normal controls for assessing the contents of triacylglycerol(TG), total cholesterol(TC), high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C),apoliprotein A-1(ApoA-1),apoliprotein B100 (ApoB100) and lipoprotein(a). RESULTS:The levels of TG,TC,LDL-C,ApoB100 and lipoprotein(a) in the patients with cerebral infarction were higher than those of the control subjects (t=2.523－ 3.796,P< 0.05);positive correlation was found between TC and age[(4.96± 1.14)mmol/L in youth vs (5.27± 1.06)mmol/L in middle age],and negative correlation between HDL-C and age[(1.39± 0.43)mmol/L in youth vs(1.26± 0.35)mmol/L in middle age];the level of lipoprotein(a) in young patients with cerebral infarction,as well as those of TG,TC,LDL-C,ApoB100 and lipoprotein-a in middle-aged patients with cerebral infarction,were significantly higher than those of the corresponding normal controls(t=2.571－ 4.107,P< 0.05);The level of lipoprotein(a) in cortex branch artery blocking subgroup was significantly higher than in penetrating artery blocking subgroup(t=5.414,P< 0.01)； no difference in serum lipids was found between initial and recurrent cerebral infarction subgroups. CONCLUSION:Lipoprotein metabolic dysfunction is a risk factor for cerebral infarction in middle age and youth. 关键词
脑梗塞/病因学/血脂/中年人/危险因素分类
医药卫生引用本文复制引用
吴军,赵水平,郭纯,蒋波,谭利明,肖志杰..血脂代谢紊乱与中青年脑梗死危险因素的相关性分析[J].中国临床康复,2004,8(1):183-185,3.
