南京医科大学学报（英文版）2007，Vol.21Issue(3)：185-189,5.
Purified protein derivative skin testing on HIV/AIDS patients and logistic regression analysis of its risk factors
Purified protein derivative skin testing on HIV/AIDS patients and logistic regression analysis of its risk factors
Fengren Liu 1Jianjun Ye 2Changfu Xiong 2Jiguo Yin 3Weihua He 3Gaobo Li 3Dingyuan Zhao 2Linxiang Ye1
作者信息
- 1. Department of Epidemiology and Biostatistics, the School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China
- 2. the Center for Disease Control and Prevention of Hubei province, Wuhan 430079, China
- 3. the Center for Disease Control and Prevention of Suizhou city, Suizhou 441300, China
- 折叠
摘要
Abstract
Objective: To understand the reactivity of purified protein derivative skin test(PPD test) in HIV-infected persons and to determine the influential factors associated with PPD. Methods: 174 HIV/AIDS patients registered in the local center for disease control and prevention(CDC) participated this study from April to June in 2006. Questionnaire, CD4 count and thoracic roentgenogram were performed for all participants. Results: In this study, response rate of questionnaires was 83.65%. The majority of these participants had a different degree of immunodeficiency that accounted for 93.64%. Female patients had a higher CD4 count than that of males. The total positive rate of PPD was 38.15%. Analysis of single factor in our study indicated that CD4 count, previous tuberculosis history, tuberculosis contact history and thoracic roentgenogram manifestation of patients were related to their PPD diameters. Further analysis of multiple factors also supports the previous conclusion that CD4 count and previous tuberculosis history of patients were risk factors in the PPD test. Conclusion: The PPD test of HIV/AIDS patients could be affected by several factors. For persons infected with HIV, the confirmation of latent tuberculosis infection (LTBI) should be considered the combination effect of previous MTB infection and body cellular immune function.关键词
HIV/AIDS/TB-infection/PPD/CD4/analysis of influential factors/latent tuberculosis infectionKey words
HIV/AIDS/TB-infection/PPD/CD4/analysis of influential factors/latent tuberculosis infection分类
医药卫生引用本文复制引用
Fengren Liu,Jianjun Ye,Changfu Xiong,Jiguo Yin,Weihua He,Gaobo Li,Dingyuan Zhao,Linxiang Ye..Purified protein derivative skin testing on HIV/AIDS patients and logistic regression analysis of its risk factors[J].南京医科大学学报（英文版）,2007,21(3):185-189,5.
