中德临床肿瘤学杂志(英文版)2004，Vol.3Issue(3)：189-191,3.
IgE骨髓瘤1例报告及文献复习
IgE Myeloma:the First Report of Chinese Case and a Review of the Literature
侯健 1HOU Jian 1姜华 2JIANG Hua 3胡慧仙 4HU Huixian 4HE Jin4
作者信息
- 1. Department of Hematology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
- 2. Department of Hematology, Jinhua Central Hospital, Zhejiang Province 321015, China
- 3. Department of Pathology, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
- 折叠
摘要
Abstract
Objective: To report a case of IgE myeloma and to compare its clinical features with those reported in the literature. Methods: M-component in serum and urine was determined using celluloseacetate membrane electrophoresis, immunofixation electrophoresis and quantification of immunoglobulins.Immunohistochemistry was performed to detect the expression of IgE and its light chain. Results: A monoclonal peak was detected by cellulose-acetate membrane electrophoresis. The monoclonal band showed on immunofixation electrophoresis the following reactive patterns: positive for λ antisera and negative for κ, IgG, IgA, IgM and IgD antisera. The serum immunoglobulin concentrations were: IgG 21.6 g/L, IgA 1.2 g/L, IgM 2.64 g/L, κ 7.49 g/L, λ 16.0 g/L, κ/λ 0.47. The results of immunohistochemistry showed cytoplasmic expression of IgE immunoglobulin and λ light chain in the tumor tissue. Conclusion: This is the first case of IgE multiple myeloma reported in China.关键词
multiple myeloma/IgE/immunohistochemistry/immunofixationKey words
multiple myeloma/IgE/immunohistochemistry/immunofixation引用本文复制引用
侯健,HOU Jian,姜华,JIANG Hua,胡慧仙,HU Huixian,HE Jin..IgE骨髓瘤1例报告及文献复习[J].中德临床肿瘤学杂志(英文版),2004,3(3):189-191,3.
