动物学研究2004，Vol.25Issue(3)：191-197,7.
弱噪声对小鼠下丘神经元频率调谐的影响
Effect of Weak Noise on the Frequency Tuning of Mouse Inferior Collicular Neurons
摘要
Abstract
In order to study the effect of weak noise on the sound signal extraction of mouse (Mus musculus Km) in ferior collicular (IC) neurons from environments, we examined the changes in frequency tuning curves (FTCs) of 32 neurons induced by a weak noise relative to 5 dB below minimum threshold of tone (reMT-5 dB) under free field stimulation conditions. The results were as follows: ① There were three types of variations in FTCs, sharpened (34.4%), broadened (18.8 %), and unaffected (46.9%), nevertheless, only the alteration of sharpened FTCs was statistically different. ② Sharpness of frequency tuning induced by a reMT-5 dB noise was very strong. Q10 and Q30 of FTCs were increased by (34.42+ 17.04)% (P =0.026, n = 11) and (46.34+22.88)% (P =0.009, n =7). ③ The changes of inverseslopes (ISs, kHz/dB) between high (IShigh) and low (ISlow) limbs of FTCs were dissymmetry. The IShigh of FTCs decreased markedly ( P = 0.046, n = 7), however, there was little change ( P = 0.947, n = 7) in ISlow. Our data revealed for the first time that the weak noise could sharpen frequency tuning and increase the sensitivity on the high frequency of sound signal in IC neurons of mouse.关键词
弱白噪声/锐化频率调谐/下丘神经元/小鼠Key words
Weak white noise/Sharpening frequency tuning/Inferior collicular neurons/Mouse分类
生物科学引用本文复制引用
唐佳,皮建辉,王丹,吴飞健,陈其才..弱噪声对小鼠下丘神经元频率调谐的影响[J].动物学研究,2004,25(3):191-197,7.基金项目
This work was supported by the National Natural Science Foundation of China (39970251) （39970251）
