摘要
Abstract
Objective: To investigate the clinical effect of the mnxifloxacin treatment for chronic obstructive pulmonary dis-ease (COPD) with acute exacerbation. Methods: 172 cases of chronic obstructive pulmonary disease in patients with acute exacerbation were randomly divided into two groups, the observation group for 86 cases, given Moxifloxacin intravenous in-jection 400 nag a day, to be treated for 5 days, then taken orally the moxifloxacin 400 rng one time a day, to be treated for 3 days;the control group for 86 cases and given intravenous levofloxacin 0.4 g one day, 5 days later changed 0.2 g, and twice a day, continutc using for 3 days; a course of observation group and control group therapy for 8 days; after 8 days, ob-served two groups patients with symptoms, signs, chest X-ray, as well as indicators such as changes in routine. Results: Moxifloxacin in the treatment of chronic obstructive pulmonary disease during acute exacerbation was significantly higher than the control group, the incidence of adverse reactions was 4.7% in the observation group, the control group was 10.5%. Conclusion: Moxifloxacin have a good effectiveness, safety and economic benefits in the treatment of chronic obstructive pulmonary disease with acute exacerbation, it is worth to promote clinical.关键词
慢性阻塞性肺疾病/急性加重/莫西沙星/临床疗效Key words
Chronic obstructive pulmonary disease/ Acute exacerbation/ Moxifloxacin/ Clinical effectiveness分类
医药卫生