中国农业科技导报2009，Vol.11Issue(3)：19-23,5.
内含肽介导的蛋白质环化研究进展
Progress of the Research on Intein-mediated Protein Cyclization
摘要
Abstract
Intein-mediated backbone cyclization of proteins is an attractive approach for stabilization of proteins against unfolding. The stabilization achieved is presumably the result of reduced conformational entropy of the unfolded state by formation of a native peptide bond between the N and C termini of a protein of interest. This approach offers a considerable promise for stabilization of pharmaceutical proteins and industrial enzymes.关键词
内含肽/蛋白质剪接/环化/稳定性Key words
intein/protein splicing/cyclization/stability分类
生物科学引用本文复制引用
赵仲麟,马鑫,林敏,平淑珍..内含肽介导的蛋白质环化研究进展[J].中国农业科技导报,2009,11(3):19-23,5.基金项目
国家863计划项目(2006AA020202)资助. （2006AA020202）
