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Association between fasting and postprandial triglyceride levels and carotid intima-media thickness in type 2 diabetes patients

陈香 田浩明 刘瑞

中华医学杂志(英文版)2003,Vol.116Issue(12):1933-1935,3.
中华医学杂志(英文版)2003,Vol.116Issue(12):1933-1935,3.

Association between fasting and postprandial triglyceride levels and carotid intima-media thickness in type 2 diabetes patients

Association between fasting and postprandial triglyceride levels and carotid intima-media thickness in type 2 diabetes patients

陈香 1田浩明 1刘瑞2

作者信息

  • 1. Department of Endocrinology,West China Hospital, Sichuan University, Chengdu 610041,China
  • 2. Laboratory of Internal Medicine,West China Hospital, Sichuan University, Chengdu 610041,China
  • 折叠

摘要

Abstract

Objective To investigate the association of fasting and postpiandial triglyceride with carotid intima-media thickness among type 2 diabetic patients in southeast China.Methods A total of 78 type 2 diabetic patients from southeast China were recruited. All the subjects underwent a standardized mixed-meal test (SMMT) and an oral glucose tolerance test. Carotid intima-media thickness (IMT) was measured by color doppler ultrasound examination.Results Postprandial triglyceride (PTG) after SMMT increased significantly in type 2 diabetic patients. The carotid IMT in patients with postprandial hypertriglyceridemia was sinificantly greater than that in patients with postprandial normal-triglyceridemia (0.90 mm vs 0.81 mm, P<0.05), which remained significant after adjustment for fasting TG and HDL-c levels, and the IMT in patients with fasting hypertriglyceridemia only had tendency to increase compared to patients with fasting normal-triglyceridemia (0.87 mm vs 0.84 mm, P>0.05).Conclusion The results suggest that postprandial hypertriglyeridemia may be an independent risk factor of early atherosclerosis in type 2 diabetes.

关键词

postprandial triglyceride/intima-media thickness/type 2 diabetes mellitus

Key words

postprandial triglyceride/intima-media thickness/type 2 diabetes mellitus

分类

医药卫生

引用本文复制引用

陈香,田浩明,刘瑞..Association between fasting and postprandial triglyceride levels and carotid intima-media thickness in type 2 diabetes patients[J].中华医学杂志(英文版),2003,116(12):1933-1935,3.

中华医学杂志(英文版)

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0366-6999

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