中国医学科学院学报2001，Vol.23Issue(2)：196-198,3.
影响凝血酶原时间国际标准化比值一致性的因素
The Factors That Influence the Consistency of International Normalized Ratio of Prothrombin Time
苏薇 1任凤琴1
作者信息
- 1. 中国医学科学院中国协和医科大学协和医院检验科,
- 折叠
摘要
Abstract
Objective To investigate the factors that influence the consistency of international normalized ra
tio (INR) of prothrombin time. Methods Using the same automated blood coagulation analyzer and
INR calibration plasma with two different types of prothrombin time (PT) reagent to assay the INR
values of 19 controls (group 1), 12 patients who took long-term anticoagulant orally (group 2),12
patients who took it at the first time (group 3) and 8 patients who took long-tern anticoagulant togeth
er with cephalosperin N (group 4). Results The two kinds of reagents gave quite different INR val
ues in all four groups (P＜0.01). The INR difference in group 3 (0.23±0.07, n = 12) was
larger than that in group 2 (0.51±0.20, n=12) (P＜0.01) .The difference in group 4
(0.61 ±0.21, n=8) was larger than that in group 2 ( P＜0.01). Conclusions The factors that may influence INR consistency are the source and sensitivity of the reagents , as well as the period
of the anticoagulant been taken and the other drugs taken at the same time.关键词
国际标准化比值影响因素口服抗凝剂分类
医药卫生引用本文复制引用
苏薇,任凤琴..影响凝血酶原时间国际标准化比值一致性的因素[J].中国医学科学院学报,2001,23(2):196-198,3.
