中国临床康复2005，Vol.9Issue(1)：200-201,2.
低氧过程中体感诱发电位的潜伏期变化
Latency changes of somatosensory evoked potential in hypoxia
摘要
Abstract
BACKGROUND: Average superposition technique is applied to acquire signals of evoked potentials(EP) in clinical practice, but it can't detect EP latency changes of every sweep in diseases. A new method of adaptive time delay estimation(TDE) can make up this shortcoming.OBJECTIVE: To observe the momentary latency changes of somatosensory evoked potentials(SEP) in hypoxia with the new TDE method.DESIGN: A randomized and controlled trial.SETTINGS and PARTICIPANTS: Experimental units: John Hopkins University of USA; Laboratory of Biomedical Signals Analysis, University of Illinois of USA; College of Electron and Information Engineering, Dalian University of Technology. Four healthy adult hybrid cats were selected from the Animal Laboratory, the Medical College of John Hopkins University of USA.INTERVENTIONS: After the anesthesia of cats, the recording electrode of SEP was placed outside the dura mater of cortex sensory area. SEP was recorded continuously before hypoxia, during hypoxia (80 mL/L O2) and after oxygen was provided( 1 000 mL/L O2) in order to analyze with TDE.MAIN OUTCOME MEASURES: The relationship between hypoxia and momentary latency changes of SEP.RESULTS: With time as the abscissa and the latency changes as the ardinate, it showed that the latency changes of SEP was close to zero before hypoxia, increased gradually under 80 mL/L O2 given, and was close to zero again under 1 000 mL/L O2 given.CONCLUSION: This new TDE method can detect instantaneous latency changes of SEP, so it can be used to observe diseases of central nervous system dynamically.关键词
诱发电位,躯体感觉/低氧/脑损伤分类
医药卫生引用本文复制引用
鲍海平,邱天爽,孔轩..低氧过程中体感诱发电位的潜伏期变化[J].中国临床康复,2005,9(1):200-201,2.基金项目
国家自然科学基金资助项目(30170259) （30170259）
