重庆医学2001，Vol.30Issue(3)：200-202,3.
常用抗厌氧菌药物对牙龈卟啉单胞菌的体外抗菌活性研究
Antibacterial activities of some commonly used antibiotics to 106 isolated strains of porphyromonas ginginalis in vitro
摘要
Abstract
Objective Porphyromonas gingivalis(Pg)is one of the main putative pathogens of periodontal disease,espcially of adult periodontitis. This in vitro study was aimed at observing the inhibition actions of 3 kinds of antimicrobial drugs on Pg. Methods 106 stains of Pg were isolated from subgingival plaques with adult periodontitis. The agar diffusion test was used to detect the inhibition actions of metronidazole,clindamycin and tinidazole on 106 stains of Pg. Results Their MIC was respectively:0. 25mg/L,0. 6rng/L. The MIC90 of tinidazole＜MIC90 of clindamycin. The results showed:all of metroidazole, tinidazole and clindamycin can be used effectively against Pg,clindarnycin and tinidazole showed more potent antibacterial activity than metronidazole. The different concentration of Pg-liquid (l05 CFU/ml, 106 CFU/ml and 108 CFU/ml) had not influenced the results. Couclusion This study is significant to antibiotical therapy of periodontal diseases.关键词
牙龈卟啉单胞菌/抗菌药物/抗菌活性分类
医药卫生引用本文复制引用
唐明,章锦才,肖晓蓉,朱珠,刘豫蓉..常用抗厌氧菌药物对牙龈卟啉单胞菌的体外抗菌活性研究[J].重庆医学,2001,30(3):200-202,3.基金项目
目家自然科学基金资助项目 （）
