湖南中医学院学报2001，Vol.21Issue(2)：20-22,3.
脑溢安对出血性中风大鼠脑内磷酸化蛋白激酶表达的影响
Effect of Nao Yi An on the Expression of P-C-Jun in the Brain of Experimental Intracerebral Hemorrhagic Rat
摘要
Abstract
To investigate the effect of traditional Chinese medicine Nao Yi An (NYA) on the expression of P-C-Jun in the brain of experimental intracerebral hemorrhagic rat.The rats were randomly divided into the normal control group,the model control group and NYA treatment group.By injecting collagenase type Ⅶ stereotaxically into the right globas pallidus,rat models with haemorrhagic stroke were made.We investigated the changes of the expression of P-CJun in the piriform cortex of the rats.Results：The expression of P-C-Jun in NYA group was weaker than that in the model control group(P＜0.05).Conclusion：NYA interferes in the expression of P-C-Jun in the brain of rat models with haemorrhagic stroke，and affects the MAPK signal transduction.关键词
脑溢安/脑出血/中风/磷酸化蛋白激酶/信号转导/平肝熄风/羚羊角/大黄分类
医药卫生引用本文复制引用
聂亚雄,黎杏群,袁梦石,张花先,张化彪,唐涛..脑溢安对出血性中风大鼠脑内磷酸化蛋白激酶表达的影响[J].湖南中医学院学报,2001,21(2):20-22,3.基金项目
国家科技部新药开发项目(96-901-05-225) （96-901-05-225）
