环境与职业医学2002，Vol.19Issue(3)：203,1.
Toxicity Studies on "840 Biologic Pesticide"
Toxicity Studies on "840 Biologic Pesticide"
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作者信息
- 1. Department of Environmental Toxicology,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030;Department of Environmental Toxicology,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030;Department of Environmental Toxicology,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030
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摘要
Abstract
[Objective] "840 Biologic Pesticide" is a very effective biologic pesticide. It consists of Abamectin and celastrus angulatus. Toxicity study was aimed to provide scientific toxicological basis. [Methods] The acute toxicity test,Ames test,micronucleus test and testicle chromosome aberration test were done. [Results] The acute toxicity of single dose of "840 Biologic Pesticide" showed that acute oral LD50 for female and male rats are 4 300 and 4 280 mg/kg,and for female and male mice are 2 330 and 5 110 mg/kg,respectively. The dermal LD50 was ＞2 000 mg/kg for female and male rats. The mutagenesis studies indicated that Ames test,micronucleus test and testicle chromosome aberration test were negative. [Conclusion] Tested pesticidc belongs to low toticity grade.关键词
biologic pesticide/acute toxicity/mutagenesis/Ames test/micronucleus/testicle chromosome aberrationKey words
biologic pesticide/acute toxicity/mutagenesis/Ames test/micronucleus/testicle chromosome aberration分类
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..Toxicity Studies on "840 Biologic Pesticide"[J].环境与职业医学,2002,19(3):203,1.
