眼科新进展2001，Vol.21Issue(3)：203-204,2.
反板层角膜移植的临床应用研究
Clinical study of reversed lamellar keratoplasty
龚岚 1朱澄 1邱孝芝 1胡麒韦 1章菊英 1付丽琴 1蒋秀丽1
作者信息
- 1. 复旦大学医学院附属眼耳鼻喉科医院眼科 200031
- 折叠
摘要
Abstract
Objective To evaluate the therapeutic efficiency of reversed lamellar keratoplasty for bullous keratopathy, Terrien's marginal degeneration and ocular chemical burns.Methods Twenty eyes of patients with bullous keratopathy, twelve eyes with Terrien's marginal degeneration, ten eyes with chemical burns were recruited in this study.Diseased tissues were removed by means of dissection.Reversed lamellae corneal tissues which had been prepared by cryopreservation were thawed and rinsed. Then the prepared posterior corneal lamellae was turned over, endothelium facing upwards. The diameter of the graft should be 0.5～1.0mm larger than that of the recipient bed. The reversed donor posterior lamellae was sutured into the host keratectomy bed with 10-0 nylon sutures continuously or interruptedly.Results Allograft reaction episode occurred only one (chemical burn) of the total 42 eyes enrolled.The grafts of the rest 41 eyes maintained clear or semitransparent for 1～5 years. Graft edema could be observed within 2～4 weeks postoperatively. Postoperative interface separation was not found. For all 20 patients with bullous keratopathy, the symptoms of pain disappeared. The visual acuity improved 2～3 lines of Snellen among eleven of twelve patients with Terrien's marginal degeneration. The visual acuity improved 2～3 lines of Snellen with four patients with chemical burns.Conclusion The technique of reversed lamellar keratoplasty can be applied successfully for tectonic reconstruction of corneal surface such as bullous keratopathy, Terrien' s marginal degeneration and also chemical burns.The effects of therapy was satisfactory.关键词
反板层角膜移植/大泡性角膜病变/Terrien's角膜变性/化学伤Key words
reversed lamellar keratoplasty/bullous keratopathy/Terrien's marginal degeneration/chemical burns分类
医药卫生引用本文复制引用
龚岚,朱澄,邱孝芝,胡麒韦,章菊英,付丽琴,蒋秀丽..反板层角膜移植的临床应用研究[J].眼科新进展,2001,21(3):203-204,2.
