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四君子汤复方总多糖对小鼠肠道粘膜相关淋巴组织的影响

刘良 周华 王培训 胡英杰

中国免疫学杂志2001,Vol.17Issue(4):204-206,3.
中国免疫学杂志2001,Vol.17Issue(4):204-206,3.

四君子汤复方总多糖对小鼠肠道粘膜相关淋巴组织的影响

Influence of total polysaccharide extracted from Sijunzi decoction on the intestinalmucosa associated lymphoid tissues of mice

刘良 1周华 2王培训 2胡英杰2

作者信息

  • 1. 香港浸会大学,
  • 2. 广州中医药大学,
  • 折叠

摘要

Abstract

Objective:By using the model of intestinal mucosal associated lymphoid tissue injury by cyclophosphamide, to understand theinfluence of total polysaccharide extracted from Sijunzi decoction (TPSJ) on the intestinal mucosal associated lympboid tissue which reflect thestatus of the intestinal mucosal immune of mice. Methods: Investigate the effects of TPSI to the number of Peyer' s aptches of mice, total cellnumber of Peyer's patches, the number of CD3+ and IgA+ cell, apoptosis at24h after being treated with 100 mg/kg cyclophosphamide.Results:TPSJ could increase the number of Peyer's patches of mice, total cell numberofPeyer's patches bea, the number of CD3+ and IgA+ cell,and could reduce apoptosia as well. Conclusion: TPSJ could antagonize the injury of intestinal mucosal associated lymphoid tissues of mice induced by cyclophosphamide, suggesting that this polysacchride can improve the intestinal mucosal immunofunction.

关键词

四君子汤多糖肠道粘膜免疫环磷酰胺

分类

医药卫生

引用本文复制引用

刘良,周华,王培训,胡英杰..四君子汤复方总多糖对小鼠肠道粘膜相关淋巴组织的影响[J].中国免疫学杂志,2001,17(4):204-206,3.

中国免疫学杂志

OA北大核心CSCD

1000-484X

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