中国动脉硬化杂志2009，Vol.17Issue(3)：206-208,3.
血浆内脏脂肪素水平与冠状动脉粥样硬化程度的相关性
Relationship Between Plasma Visfatin Level and Coronary Artery Atherosclerosis in Patients with Coronary Artery Diseases
摘要
Abstract
Aim To explore the relationship between plasma visfatin level and coronary artery atherosclerosis (As) in patients with coronary artery diseases (CAD). Methods 62 causes were undergone coronary angiography and divided into control group of 13 cases and As group of 49 cases. The severity of coronary stenosis was determined by Gensini score and based on the results, the As group were classified into two sub-groups: mild and severe groups. The plasma levels of visfatin were measured by ELISA kits. Results Compared with control group, plasma level of visfatin was significantly elevated in As group. In As groups, patients with severe As have higher plasma level of visfatin than those in patients with mild As. Moreover, plasma level of visfatin was positively correlated with Gensini (r=0.359, P<0.01). Conclusions The plasma level of visfatin is closely correlated with the severity of coronary artery in CAD patients, suggesting that visfatin may be involved in the process of As.关键词
冠状动脉粥样硬化/内脏脂肪素/Gensini积分Key words
Visfatin/Atherosclerosis/Gensini Score分类
医药卫生引用本文复制引用
曹宇,肖丽,姜德建,肖坚..血浆内脏脂肪素水平与冠状动脉粥样硬化程度的相关性[J].中国动脉硬化杂志,2009,17(3):206-208,3.基金项目
国家自然科学基金项目(30700319、30800477),国家大学生创新性实验计划项目(081053349) （30700319、30800477）
