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加拿大红豆杉扦插苗中的化学成分研究

李力更 涂光忠 金怡珠 张嫚丽 顾玉诚 史清文

天然产物研究与开发2007,Vol.19Issue(2):211-215,5.
天然产物研究与开发2007,Vol.19Issue(2):211-215,5.

加拿大红豆杉扦插苗中的化学成分研究

Taxane Diterpenoids from the Rooted Cuttings of Taxus canadensis

李力更 1涂光忠 2金怡珠 2张嫚丽 1顾玉诚 1史清文3

作者信息

  • 1. 河北医科大学药学院天然药物化学教研室,石家庄,050017
  • 2. 北京微量化学研究所,北京,100091
  • 3. 先正达集团英国国际研究中心天然产物部,英国RG42 6EY
  • 折叠

摘要

Abstract

Three taxane diterpenoids were isolated from Taxus canadensis rooted cuttings. The structures were determined to be taxuspine U (1) ,taxezopidine U (2) ,and amine salt of taxuspine H (3) on the basis of 1D- and 2D NMR spectral analysis. All of them were isolated for the first time from the Canadian yew. The original assignments of H-9,H-10and C-9 ,C-10 in taxuspine H should be exchanged according to HMBC experiment.

关键词

加拿大红豆杉/化学成分/紫杉烷二萜/扦插苗

Key words

Taxus canadensis/Taxaceae/yew/taxane/rooted cutting

分类

医药卫生

引用本文复制引用

李力更,涂光忠,金怡珠,张嫚丽,顾玉诚,史清文..加拿大红豆杉扦插苗中的化学成分研究[J].天然产物研究与开发,2007,19(2):211-215,5.

基金项目

Acknowledgements This work was supported by the Foundation for Developing New Drugs of People's Republic of China (No:2003AA2Z3527) and the Scientific Research Foundation for the Returned Overseas Chinese Scholars,State Education Ministry of P.R.China.Syngenta research foundation(2005-Hebei Medical University-Syngenta-01)was also acknoledged. (No:2003AA2Z3527)

天然产物研究与开发

OACSCDCSTPCD

1001-6880

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