中国实用内科杂志2001，Vol.21Issue(1)：21-22,2.
低潮气量加呼气末正压通气对急性肺损伤氧代谢的影响
Effect of low tidal volume with positive end-expiratory pressure on oxygen metabolism in patients with acute lung injury
摘要
Abstract
Objective To explore the effect of low tidal volume with positive end-expiratory pressure (PEEP) on oxygen metabolism in 14 acute lung injury (ALI) patients.Methods 14 patients with ALI were optimally ventilated by Assist and Control(A/C),and PEEP was increased gradually for 30min,respectively.The concentration of FiO2 was kept constant.The parameters of oxygen metabolism were obtained by using Swan-Ganz catheter.Results At PEEP 1.47kPa,the maximal DO2 was obtained,the DO2 was decreased at PEEP 1.96kPa (P<0.05).MBP,PAP and CI were not significantly different from PEEP 0.49～1.47kPa(P<0.05).CI decreased at PEEP 1.96kPa(P<0.05).Cst was kept approximately(33.6±8.3)mL/cmH2O from PEEP 0.98 to 1.47kPa,but Cst was decreased at PEEP 1.96kPa(P<0.05).Conclusion The low tidal volume with a given PEEP can obtain constant Cst and reduce the effect on hemodynamics in patients with ALI,and obtain the maximal DO2.关键词
低潮气量/呼气末正压/氧代谢分类
医药卫生引用本文复制引用
刘长文,秦宗和,王海燕,周明根..低潮气量加呼气末正压通气对急性肺损伤氧代谢的影响[J].中国实用内科杂志,2001,21(1):21-22,2.
