中国免疫学杂志2001,Vol.17Issue(4):212-214,217,4.
TAP1基因和FcεRIβ基因多态性与哮喘及其表型的相关性研究
The association analysis of TAP1 gene, FcεRIβ gene with asthma and its phenotype
徐青 1邓伟吾 1李伟杰 1黄绍光 1张洪熹 2孙碧雄2
作者信息
- 1. 上海第二医科大学瑞金医院肺科,
- 2. 海纺织局第一医院分子生物学中心,
- 折叠
摘要
Abstract
Objective:In order to known the relationship between TAP1 gene, FcεRIβand the development of asthma.Methods:Themicrosatete TAP1 inside the intron of TAP1 gene and the RFLP locus inside the intron of FcεRIβgene were choiced to study in asthma patients using the Amp-FLP and RFLP method.Results: The allels of FcεRlβgene is associated with asthma and BHR, there is not relationship between TAP1 and asthma.Conchusion:FcεRIβgene may be important candidate gene susceptibility to asthma. TAP1 gene may not participate inthe devclopment of asthma.关键词
哮喘TAP1基因FcεRIβ基因相关分析分类
医药卫生引用本文复制引用
徐青,邓伟吾,李伟杰,黄绍光,张洪熹,孙碧雄..TAP1基因和FcεRIβ基因多态性与哮喘及其表型的相关性研究[J].中国免疫学杂志,2001,17(4):212-214,217,4.