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TAP1基因和FcεRIβ基因多态性与哮喘及其表型的相关性研究

徐青 邓伟吾 李伟杰 黄绍光 张洪熹 孙碧雄

中国免疫学杂志2001,Vol.17Issue(4):212-214,217,4.
中国免疫学杂志2001,Vol.17Issue(4):212-214,217,4.

TAP1基因和FcεRIβ基因多态性与哮喘及其表型的相关性研究

The association analysis of TAP1 gene, FcεRIβ gene with asthma and its phenotype

徐青 1邓伟吾 1李伟杰 1黄绍光 1张洪熹 2孙碧雄2

作者信息

  • 1. 上海第二医科大学瑞金医院肺科,
  • 2. 海纺织局第一医院分子生物学中心,
  • 折叠

摘要

Abstract

Objective:In order to known the relationship between TAP1 gene, FcεRIβand the development of asthma.Methods:Themicrosatete TAP1 inside the intron of TAP1 gene and the RFLP locus inside the intron of FcεRIβgene were choiced to study in asthma patients using the Amp-FLP and RFLP method.Results: The allels of FcεRlβgene is associated with asthma and BHR, there is not relationship between TAP1 and asthma.Conchusion:FcεRIβgene may be important candidate gene susceptibility to asthma. TAP1 gene may not participate inthe devclopment of asthma.

关键词

哮喘TAP1基因FcεRIβ基因相关分析

分类

医药卫生

引用本文复制引用

徐青,邓伟吾,李伟杰,黄绍光,张洪熹,孙碧雄..TAP1基因和FcεRIβ基因多态性与哮喘及其表型的相关性研究[J].中国免疫学杂志,2001,17(4):212-214,217,4.

中国免疫学杂志

OA北大核心CSCD

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