中南民族大学学报（自然科学版）2002，Vol.21Issue(4)：21-24,4.
阿斯匹林的热稳定性及其热解动力学
Thermal Stabilities and the Thermal Decomposition Kinetics of Aspirin Drug
张健 1吴士筠 1陈栋华2
作者信息
- 1. CollegeofChemandLifeScience,SCUFN
- 折叠
摘要
Abstract
Purpose: to study aspirin drugs′ thermal process and kinetics of thermal decomposition. Methods: to investigate the non-isothermal kinetics of thermal decomposition of aspirin drugs with Freeman-Carrollde method and Ozawa method by TG techniques and to determine drugs′ stability by comparing their data of activation energy and temperatures of their thermal decomposition. Results:the thermal decomposition processes and mechanism functions of drugs were suggested, and their activation energy(E), reaction order(n) and frequency factor(A) were also obtained respectively. The thermal decomposition kinetics equation of aspirin can be expressed as: dα/dt=1.15×108e-96.04/RT (1-(α)1.91. Conclusion: stability of the tablets is bigger than that of materials. Being sensitive to temperature, it is suggested that aspirin should be stored in low temperature properly. The shelf life that aspirin decomposes 10 % at room temperature is estimated 2.08 a.关键词
阿斯匹林/热重分析/热稳定性/非等温动力学/保存期Key words
aspirin/TG(thermogravimetry)/thermal stability/non-isothermal kinetics/shelf-life time分类
化学化工引用本文复制引用
张健,吴士筠,陈栋华..阿斯匹林的热稳定性及其热解动力学[J].中南民族大学学报（自然科学版）,2002,21(4):21-24,4.
