中国药科大学学报2001,Vol.32Issue(1):21-24,4.
可生物降解丹参药膜的体外释药研究
Studies on the Release Behavior in vitro of Biodegradable Salvia miltiorrhiza Film
摘要
Abstract
AIM:To study the release properties in vitro of Salviamiltiorrhiza film prepared with chitosan. METHODS: Determining the release kinetics of tanshinone ⅡA and cryptotanshione from the film at 37.5℃ appropriate recipient by HPLC. RESULTS: Release of tanshinone ⅡA agrees with Higuchi equation while cryptotanshinone performs a significant first burst effect in the very first day. CONCLUSION: The film can sustain the release of tanshinone ⅡA but hasn′t the same impact on cryptotanshinone.关键词
丹参/生物降解膜/壳聚糖/释放度分类
医药卫生引用本文复制引用
王凯,赵浩如,肇毅,潘立群..可生物降解丹参药膜的体外释药研究[J].中国药科大学学报,2001,32(1):21-24,4.基金项目
国家中医药管理局基金项目[97Z104] ()