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Isolation of a novel antifungal peptide from the bark of Eucommia ulmoides Oliv

Liu Shihui Zhao Degang Han Yuzhen

高技术通讯（英文版）2008，Vol.14Issue(2)：216-219,4.

Isolation of a novel antifungal peptide from the bark of Eucommia ulmoides Oliv

Liu Shihui ¹Zhao Degang ²Han Yuzhen¹

作者信息

1. Guizhou Key Laboratory of Agricultural Bioengineering, College of Life Sciences, Guizhou University, Guiyang 550025, P.R.China
2. Key Laboratory of Green Pesticide and Agricultural Biological Engineering, Ministry of Education, Guizhou University, Guiyang 550025, P.R.China
折叠

摘要

Abstract

A novel Eucommia antifungal peptide, named EAFP3, was isolated from the bark of Eucommia ulmoides by NaCl extract, gel filtration and reverse phase high performance liquid chromatography. The molecular mass of EAFP3 is 4157.3 Da, and its partial amino acid sequence is -.LYQQLIAGITLNK.-. EAFP3 exerts an inhibitory activity against Candida albicans in vitro and the drug concentration required for 50% growth inhibition (IC50) is 31.25μg/mL.

关键词

antifungal peptide/isolation/the bark of Eucommia ulmoides Oliv/Candida albicans

Key words

antifungal peptide/isolation/the bark of Eucommia ulmoides Oliv/Candida albicans

分类

化学化工

引用本文复制引用

Liu Shihui,Zhao Degang,Han Yuzhen..Isolation of a novel antifungal peptide from the bark of Eucommia ulmoides Oliv[J].高技术通讯（英文版）,2008,14(2):216-219,4.

基金项目

Supported by the National Natural Science Foundation of China (30660146) and the Ministry of Sciences of Technology Program of China (2003CCA02600). （30660146）

高技术通讯（英文版）

OAEI

ISSN：1006-6748

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