中国病理生理杂志2001，Vol.17Issue(3)：219-222,4.
53BP1和53BP2基因在鼻咽癌
组织中表达的研究
The expression of 53BP1 and 53BP2 gene in nasopharyngeal carcinoma
李虹 1张玲 1杨旭宇 1韩为农 1周文 1姚开泰1
作者信息
摘要
Abstract
AIM: To investigate the expression map of two p53 binding proteins 53BP1 and 53BP2 in nasopharyngeal carcinoma (NPC) tissue.METHODS: The expression of 53BP1 and 53BP2 mRNA in NPC biopsy and control group are tested by RT-PCR. The expression of two mRNA in NPC paraffin section are examined by in situ hybridization. RESULTS: No expression of 53BP1 mRNA was found in NPC tissue and control group. However, expression of 53BP2 was detected in NPC biopsy and control group by RT-PCR, specific expressoin found cancerous nest in NPC paraffin section by in situ hybridization.CONCLUSION: The high expression of 53BP2 may be related to the development of NPC.关键词
鼻咽癌/基因,p53/基因表达分类
生物科学引用本文复制引用
李虹,张玲,杨旭宇,韩为农,周文,姚开泰..53BP1和53BP2基因在鼻咽癌
组织中表达的研究[J].中国病理生理杂志,2001,17(3):219-222,4.
