白求恩医科大学学报2001，Vol.27Issue(1)：22-23,2.
人外周血淋巴细胞膜电压依赖性钾通道特性分析及试分型
Property analysis of voltage-dependent potassium channel in human peripheral blood lymphocytes and its subset
孙晓霞 1宋洪臣 2周庆伟 3何艳 1钟国赣1
作者信息
- 1. 吉林大学基础医学院生理教研室,
- 2. 吉林大学第一医院康复科
- 3. 吉林大学成人教育学院
- 折叠
摘要
Abstract
Objective:To analyse the property of voltage-dependent potassium 〔K(v)〕 channel in healthy people′s peripheral lymphocyte so as to contribute the control for property alteration under some pathological condition,and to try to find the new subset of this channel.Methods:Patch-clamp whole cell recording technique was used.Results:In the recorded 39 cells,activated voltage of the channels was -40.3±2.5 Mv.No inactivation phenomenon appeared under repeated stimulation.The closing time of the channels was 116.3+8.2 ms under the repolarization,and the current could be inhibited by 10 mmol/L TEA.Conclusion:There might be only one type of K(v) channel in human peripheral blood lymphocytes,and its properties quite resumble the type of n K(v) channel in mice.关键词
膜片钳/电压依赖性钾通道/人外周血淋巴细胞分类
生物科学引用本文复制引用
孙晓霞,宋洪臣,周庆伟,何艳,钟国赣..人外周血淋巴细胞膜电压依赖性钾通道特性分析及试分型[J].白求恩医科大学学报,2001,27(1):22-23,2.
