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Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury

CAO Fu-jiang FENG Shi-qing

中华医学杂志(英文版)2009,Vol.122Issue(2):225-231,7.
中华医学杂志(英文版)2009,Vol.122Issue(2):225-231,7.DOI:10.3760/cma.j.issn.0366-6999.2009.02.021

Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury

Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury

CAO Fu-jiang 1FENG Shi-qing1

作者信息

  • 1. Department of Orthopaedics, General Hospital of Tianjin Medical University, Tianjin 300052, China
  • 折叠

摘要

Abstract

Objective To review the recent studies about human umbilical cord mesenchymal stem cells (hUCMSCs) and advances in the treatment of spinal cord injury, Data sources Published articles (1983-2007) about hUCMSCs and spinal cord injury were selected using Medline. Study selection Articles selected were relevant to development of mesenchymal stem cells (MSCs) for transplantation in spinal cord injury therapy. Of 258 originally identifiied arises 51 were selected that specifically addressed the stated purpose. Results Recent work has revealed that hUCMSCs share most of the characteristics with MSCs derived from bone marrow and are more appropriate to transplantation for cell based therapies. Conclusions Human umbilical cord could be regarded as a source of MSCs for experimental and clinical needs. In addition, as a peculiar source of stem cells, hUCMSCs may play an important role in the treatment of spinal cord injury.

关键词

umbilical cord/mesenchyrnal stem cells/spinal cord injuries

Key words

umbilical cord/mesenchyrnal stem cells/spinal cord injuries

分类

医药卫生

引用本文复制引用

CAO Fu-jiang,FENG Shi-qing..Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury[J].中华医学杂志(英文版),2009,122(2):225-231,7.

基金项目

This study was supported by the grants from National Natural Science Foundation of China (No. 30872603), New Century Excellent Talents Programme of Ministry of Education of China(No. NCET060251) and Applied Basic Research Programmes of Science and Technology Commission Foundation of Tianjin (No.07JCYBJC10200). (No. 30872603)

中华医学杂志(英文版)

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