摘要
Abstract
Objective: To evaluate the clinical effect of integrated traditional Chinese medicine and western Medicine (TCM-MW) and to investigate effective therapy of TCM for lupus nephritis (LN). Methods: We performed a me ta-analyses to analyze total 2160 patients with LN [1186 patients treated with TCM-WM (CW group) and 974 patients treated with western medicine alone (W group)] from 22 published randomized and controlled trials that were included by Chinese Biology Medicine disc from 1990 through 2002. Results: The total effective rate and the whole remission rate of CW group were significantly higher than that of W group (94.1% vs 79.0%, 34.4% vs 20.3%) and the inefficacy, mortality, recurrent rate and adverse reaction rate were much lower than W group (5.6% vs 18.1%,0.3% vs 3.0%. 5.9% vs 22.8%, 27.7% vs 71.8% respectively). 2. Frequency that major traditional Chinese medicine was used: herb of spneading hedyotis, radix arnebiae, herb of barbed skullcap, centipede, motherwort herb, root of dan-shen, radix paeoniae rubra was 85.7%, 81.3%, 76.7%, 73.3%, 81.2%, 87.2% and 72.0% respectively. Conclusions: Using clearing away heat and toxic material, activating blood circulation to dissipate as central TCM-MM therapy were obviously superior to therapy with western medicine alone.关键词
中西医结合/狼疮性肾炎/荟萃分析Key words
integrated traditional/chinese medicine and western medicine/lupus nephritis/meta-analysis分类
医药卫生
