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重症肌无力胸腺切除术后远期预后生存分析

刘伟 佟倜 纪振东 张振和

中华医学杂志(英文版)2002,Vol.115Issue(2):235-237,3.
中华医学杂志(英文版)2002,Vol.115Issue(2):235-237,3.

重症肌无力胸腺切除术后远期预后生存分析

Long-term prognostic analysis of thymectomized patients with myasthenia gravis

刘伟 1佟倜 1纪振东 1张振和1

作者信息

  • 1. 白求恩医科大学第一临床学院胸外科,长春,130021
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摘要

Abstract

Objective To study the factors affecting the long-term prognosis of patients with myasthenia gravis (MG) after thymectomy.Methods 170 MG patients who had undergone thymectomies were studied retrospectively. Among them, 124 patients received long-term follow-up for more than 40 months postoperatively. The COX regression analysis model was used to analyze the factors that may influence the long-term prognosis. These factors included thymus pathology, patient gender, age, duration of disease at the time of surgery, preoperative Osserman classification and medication.Results The research showed that thymus pathology was the single independent factor that affected the postoperative long-term prognosis. The long-term survival rates differed significantly with thymus pathological types: hyperplasia > benign thymoma > atrophy > malignant thymoma (P<0.05).Conclusion The different pathological types of the thymus were the important factor affecting long-term survival in MG patients after thymectomy.

关键词

重症肌无力/胸腺切除术/病理/预后

Key words

myasthenia gravis/thymectomy/pathology/prognosis

分类

医药卫生

引用本文复制引用

刘伟,佟倜,纪振东,张振和..重症肌无力胸腺切除术后远期预后生存分析[J].中华医学杂志(英文版),2002,115(2):235-237,3.

基金项目

This work was supported by a grant from the Jilin Provincial Health Bureau (No. 005). (No. 005)

中华医学杂志(英文版)

OAMEDLINESCI

0366-6999

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