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反丁烯二酸桂醇甲酯的合成及抗菌活性研究

战宇 宁正祥

云南农业大学学报2006,Vol.21Issue(2):239-242,4.
云南农业大学学报2006,Vol.21Issue(2):239-242,4.

反丁烯二酸桂醇甲酯的合成及抗菌活性研究

Synthesis Technology and Antimicrobial Activity of Cinnamyl Methyl Fumarate

战宇 1宁正祥2

作者信息

  • 1. 广州大学生物与化学工程学院,广东,广州,510091
  • 2. 华南理工大学轻工食品学院,广东,广州,510640
  • 折叠

摘要

Abstract

Synthesis technology of cinnamyl methyl fumarate (CMF) containing α,β-unsaturated carbonyl group and its antimicrobial activity was studied.Mono-cinnamyl maleate was prepared by esterification of maleic anhydride and cinnamyl alcohol of 1 mol:2 mol at 95 ℃ for 2~4 h.Then added isomeric catalyst and mono-cinnamyl fumarate was made by reacting at 90 ℃ for 4 h.After methanol (methanol:mono-cinnamyl fumarate = 6 mol:1 mol) was added,the mixture maintained at 90 ℃ for 4.0 h to synthesize CMF.Skin test indicated that CMF has no cutaneous anaphylaxis.Antimicrobial study showed that CMF could remarkably inhibit the growth of mold,yeast and bacteria.These suggested CMF was a preservative worth of developing and applying largely in food processing.

关键词

防腐剂/反丁烯二酸桂醇甲酯/合成/抗菌活性

Key words

preservative/cinnamyl methyl fumarate/synthesis/antimicrobial activity

分类

轻工纺织

引用本文复制引用

战宇,宁正祥..反丁烯二酸桂醇甲酯的合成及抗菌活性研究[J].云南农业大学学报,2006,21(2):239-242,4.

云南农业大学学报

1004-390X

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