中国临床康复2005，Vol.9Issue(32)：240-242,3.
在体兔脑组织电阻抗频率特性测量及电阻抗断层成像
In vivo measurement of the rabbit brain impedance frequency response and the elementary imaging of electrical impedance tomography
摘要
Abstract
BACKGROUND: Electrical impedance tomography (EIT) uses non-invasive signals to probe the human body and then detect the responses on the boundary of the body in order to reconstruct an impedance distribution inside the body. Compared to CT and MRI, EIT takes the advantages of realtime technique, lower cost and easiness for both continuous monitoring and functional imaging.OBJECTIVE: This study was designed to perform the in vivo measurement of the rabbit brain impedance frequency response before and after ischemia. And it was to verify the feasibility of EIT in brain functional imaging by ischemia brain functional imaging using EIT.DESIGN: It was a single-sample experiment.SETTING: It was conducted at the Department of Medical Electronic Engineering, Faculty of Biomedical Engineering, Fourth Military Medical University of Chinese PLA.MATERIALS: This study was conducted at the Department of Medical Electronic Engineering, Faculty of Biomedical Engineering, Fourth Military Medical University of Chinese PLA from August to September 2001 and 10 healthy rabbits were selected.METHODS: Cerebral ischemia animal model was made using carotid artery ligation. Then the in vivo measurement of the rabbit brain impedance frequency response before and after ischemia was performed.Dynamic unilateral brain blood supply was recorded using EIT imaging.curves were plot before and after ischemia in the frequency range from 0.1 Hz EIT imagingRESULTS: Nine rabbits entered the statistical analysis and one was omitimpedance increased significantly. The ratio of increasing impedance can be up to 75% at frequencies lower than 10 Hz. And in the range from 1 kHz namic imaging showed that the changes in unilateral brain blood supply is accordant with the corresponding regions having a changing impedance.CONCLUSION: The changes in brain tissue impedance before and after ischemia can be imaged and it could be used as a variable for EIT imaging.关键词
脑/电阻抗/体层摄影术/信号处理/计算机辅助分类
医药卫生引用本文复制引用
吴小明,董秀珍,秦明新,王跃民..在体兔脑组织电阻抗频率特性测量及电阻抗断层成像[J].中国临床康复,2005,9(32):240-242,3.基金项目
中国-以色列科学与战略研究开发专项资金合作研究项目(99M-0021426) Supported by: the Grants from Cooperation Study Program of Science and Strategy Development of China and Israel, No. 99M-002 1426 （99M-0021426）
