中德临床肿瘤学杂志（英文版）2006，Vol.5Issue(4)：240-244,5.
Lung Cancer Survival Improvement through Surgical Intervention in PUMCH Hospital
Lung Cancer Survival Improvement through Surgical Intervention in PUMCH Hospital
GUO Feng 1ZHANG Zhiyong 1CUI Yushang 1LI Shanqing 1LI Li 1XU Xiaohui 1GE Feng 1GUO Huiqin 1LI Zejian1
作者信息
- 1. Department of Thoracic Surgery, PUMC Hospital, Beijing 100730, China
- 折叠
摘要
Abstract
Objective: To investigate and evaluate improvement of lung cancer survival after surgical intervention in PUMC hospital during the last 15 years. Methods: From January 1989 to December 2003, 1574 lung cancer cases underwent surgical treatment and followed up. All cases in this series were divided into two groups according to time period: group A (1999-2003) and group B (1989-1998). The difference in the survival rate between groups A and B was compared. Results: The morbidity and mortality in group A was decreased significantly in comparison to group B (11.2% vs. 19.2%, 1.06% vs. 1.93%, respectively).However, the 3-year and 5-year survival rate was increased from 42.35% to 56.07%, and from 28.46% to38.99%, respectively. A significant improvement in survival was observed in patients with stage Ⅰ, Ⅱ and ⅢA, but not in those with stage ⅢB and Ⅳ. Also, patients with lobectomy had more satisfactory results than those receiving exploratory thoracotomy, limited resection, pneumonectomy and sleeve resection. Conclusion: Lobectomy plus systematic mediastinal lymph nodes dissection has become the standard mode for resectable lung cancer. Combination of complete resection along with lymph nodal dissection, and postoperative adjuvant chemotherapy based on platinum/3rd generation chemotherapy medicine, has preliminarily been justified, proving an important approach for effective improvement in long-term survival of non-small cell lung carcinoma.关键词
lung neoplasm/surgery/lobectomyKey words
lung neoplasm/surgery/lobectomy分类
医药卫生引用本文复制引用
GUO Feng,ZHANG Zhiyong,CUI Yushang,LI Shanqing,LI Li,XU Xiaohui,GE Feng,GUO Huiqin,LI Zejian..Lung Cancer Survival Improvement through Surgical Intervention in PUMCH Hospital[J].中德临床肿瘤学杂志（英文版）,2006,5(4):240-244,5.
