中德临床肿瘤学杂志（英文版）2007，Vol.6Issue(3)：241-244,4.
食管癌术后辅助化疗价值的Meta分析
Surgery with and without chemotherapy for localized carcinoma of esophagus:a meta-analysis
Weizhao Huang 1Jianhua Fu 1Yi Hu 1Xu Zhang 1Hong Yang 1Bin Zheng 1Geng Wang1
作者信息
- 1. State Key Laboratory of Oncology in Southern China,Department of Thoracic Surgery,Cancer Center,Sun Yat-Sen University,Guangzhou 510060,China
- 折叠
摘要
Abstract
Objective:To evaluate the efficacy of adjuvant chemotherapy in patients with esophageal carcinoma undergoing radical surgery by meta-analysis.Methods:CBMDisc.CNKI,Pubmed databases were searched from January 1995 to June 2005.Randomized trials on comparison surgery plus adjuvant chemotherapy(S+C)and surgery alone for patients with localized carcinoma of esophaqus were selected.RevMan 4.2 software was used for meta-analysis.Results:7 studies were included in the meta-analysis.A total of 401 patients underwenl radical surgery plus chemotherapy and 463 underwent surgery alone.Compared with surqery alone.the patients underwent S+C were significantly superior in the 3-year survival rate:the combined relative risk(RRs) of death was 0.83,95%confidence interval(CI)was 0.71 to 0.95,P=0.009.Conclusion:Based on the review.adjuvant chemotherapy has a benefit on the 3-year survival rate in the patients with esophageal carcinoma.关键词
esophageal neoplasm/adjuvant chemotherapy/meta-analysisKey words
esophageal neoplasm/adjuvant chemotherapy/meta-analysis分类
医药卫生引用本文复制引用
Weizhao Huang,Jianhua Fu,Yi Hu,Xu Zhang,Hong Yang,Bin Zheng,Geng Wang..食管癌术后辅助化疗价值的Meta分析[J].中德临床肿瘤学杂志（英文版）,2007,6(3):241-244,4.
