Blockage of PI3K/PKB/P27kip1 signaling pathway can antagonize 17β-estradiol-induced Ishikawa proliferation and cell cycle progressionOACSTPCD
Blockage of PI3K/PKB/P27kip1 signaling pathway can antagonize 17β-estradiol-induced Ishikawa proliferation and cell cycle progression
It is well-known that risk for endometrial adenocar- cinoma increases in patients with high level of estrogen that is unopposed by progestin. And activation of extracellular signal-regulated kinase (ERK)1 and phosphatidylino…查看全部>>
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Department of Gynecology, People's Hospital, Peking University, Beijing 100044, China;Department of Obstetrics and Gynecology, First Teaching Hospital, Zhengzhou University, Zhengzhou 450052, China;Department of Gynecology, People's Hospital, Peking University, Beijing 100044, China;Department of Obstetrics and Gynecology, First Teaching Hospital, Zhengzhou University, Zhengzhou 450052, China;Department of Gynecology, People's Hospital, Peking University, Beijing 100044, China;Department of Internal Medicine, People's Hospital, Peking University, Beijing 100044, China
医药卫生
endometrial neoplasmsestrogenssignal transduction pathwaycell cyclecell proliferation
endometrial neoplasmsestrogenssignal transduction pathwaycell cyclecell proliferation
《中华医学杂志(英文版)》 2006 (3)
242-245,4
This study was partially supported by a grant from the Scientific Research Fund for Capital Medicine Development (No.ZD 199911).
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